Best nootropics for sleep in 2022

There are many nootropics that have been shown to improve sleep quality. These nootropics can help improve your overall sleep quality, help you fall asleep faster, and keep you sleeping through the night. Some of the best nootropics for sleep in 2022 will be discussed in this article, so continue reading to learn more!

Best nootropics for sleep deprivation supplements

Nootropics for a good night's sleep

Sleep deprivation is a common problem that many people face. The lack of sleep due to poor sleep patterns can lead to health problems, decreased productivity, and in some cases, death. While there are many ways to try to improve sleep, such as establishing a bedtime routine or avoiding caffeine before bed, some people find that they still struggle with getting enough sleep.

In these cases, it may be helpful to try taking nootropics for sleep supplements. There are two types of nootropics for good sleep, the brain chemicals and the natural nootropics.

Brain chemicals for good sleep

Nootropics are a type of supplement that is designed to improve cognitive function. Some nootropics are also known for their ability to help people fall asleep and stay asleep. There are many different types of nootropics that can be used for this purpose, but some of the most popular include norepinephrine, cortisol, melatonin, serotonin, GABA, and acetylcholine.



Norepinephrine has been shown to be effective in promoting healthy sleep. In a study of 43 people, those who took norepinephrine for four weeks slept better and felt more alert during the day than those who took a placebo.

This effect is thought to be due to the boost in serotonin and dopamine levels that norepinephrine can provide. Norepinephrine also works by blocking certain neurotransmitters that are involved in sleep regulation.

There is no one definitive answer to the question of how much norepinephrine is necessary for good sleep. However, studies have shown that a dosage of around 0.3 milligrams can be effective for some people. Norepinephrine helps to regulate the body’s natural sleep-wake cycle, and low levels can lead to difficulty falling or staying asleep.


Cortisol is a hormone that is produced by the adrenal gland. It is often called the stress hormone because it is released in response to stress. Cortisol plays many important roles in the body, including regulating blood pressure and glucose levels, and helping the body respond to stress. Recent research suggests that cortisol may also play a role in sleep.

Studies have shown that cortisol levels are highest just before bedtime. This may be why people with high levels of cortisol often have difficulty falling asleep or staying asleep and disrupts sleep stages. Some researchers believe that reducing cortisol levels may help improve sleep quality. There are currently several ways to reduce cortisol levels, including exercise, relaxation techniques, and supplements.


Melatonin sleep supplement

There’s a reason why melatonin is often called the “sleep hormone.” This brain chemical promotes REM sleep, responsible for maintaining your body’s circadian rhythm, ensuring you get the right amount of shuteye each night. Production of melatonin peaks in the evening, just as darkness starts to fall, making it easier to nod off.

Studies have also shown that taking melatonin supplements can help improve sleep quality and duration. If you’re having trouble sleeping, consider talking to your doctor about trying out a melatonin supplement.

The dose of melatonin supplement needed to achieve these benefits varies from person to person, so it may take some trial and error to find the right dosage for you. Most people start with a dose of 0.5 to 1 milligram and increase it if needed.

It is important to note that melatonin should not be taken everyday, but only as needed for sleep problems. Taking too much can cause drowsiness, headaches, and nausea.


Serotonin brain chemical

Serotonin is a neurotransmitter that helps regulate mood, appetite, and sleep. It’s believed that serotonin plays a role in promoting quality sleep by helping to increase the overall quality of sleep. Serotonin also helps to reduce stress levels, which can help improve sleep quality.

In relation, serotonin supplements are becoming popular for treating insomnia. A recent study found that a dosage of 20-40 mg was effective in improving sleep quality in adults. However, more research is needed to determine the long-term effects of serotonin supplements on sleep.


GABA, or gamma-aminobutyric acid, is a neurotransmitter that is produced in the brain. It has been shown to help promote good sleep by regulating sleep duration, inducing a calm state, and helping to block nerve impulses that can cause anxiety and stress. Low levels of GABA are often associated with insomnia and other sleep disorders. Supplementing with GABA may help to improve sleep quality and duration.


Dopamine brain chemical

The neurotransmitter dopamine is responsible for feelings of pleasure and reward. New research suggests that this brain chemical may also work to promote good sleep. Researchers found that when rats with depleted levels of dopamine were given a compound that activates dopamine receptors, they slept more soundly and for longer periods of time. The study’s authors say the findings could lead to new treatments for sleep disorders caused by dopamine depletion, such as Parkinson’s disease.


Acetylcholine brain chemical

The neurotransmitter acetylcholine is responsible for many bodily functions, including sleep. Acetylcholine receptors are located in many parts of the brain, including the hypothalamus, which is responsible for regulating sleep. When acetylcholine binds to these receptors, it initiates a series of events that lead to good night sleep.

One such event is the release of melatonin, a hormone that helps regulate the body’s internal clock and promote sleep. Acetylcholine may also help to increase deep sleep and reduce nighttime awakenings.

Acetylcholine supplements are available at many health food stores and online. The most common side effects of acetylcholine supplements are gastrointestinal problems such as nausea, vomiting, and diarrhea.

Natural nootropics for sleep

While many nootropics are synthetic, some natural nootropics can also help promote better sleep. These include l-tryptophan, lemon balm, l-theanine, bacopa monnieri, and magnesium. These nootropics have been shown to promote relaxation and reduce anxiety, which can help lead to a more restful night’s sleep.


L-tryptophan is an amino acid that is found in many foods, including turkey, chicken, and cheese. It has been shown to help with stress and relaxation for easier sleep onset thus promoting sleep, especially when consumed along with carbohydrates. L-tryptophan helps to produce serotonin, a hormone that promotes relaxation and sleepiness. When consumed before bedtime, l-tryptophan can help you fall asleep faster and get a better night’s sleep.

Low levels of L-tryptophan have been seen in people with depression. Some claim up to 60 milligrams of L-tryptophan daily may help improve your mood or ward off mental health disorders such as depression. However, there is limited research to back these claims and studies show mixed results in supporting these claims.

On the other hand, L-tryptophan can interfere with many different medicines and has been linked to a dangerous, even deadly condition called eosinophilia-myalgia syndrome. Always tell your doctor about any supplements you are taking, including natural ones and those bought without a prescription. That way, your doctor can check on any potential side effects or interactions with any medications.

Lemon balm

Lemon balm for quality sleep

Lemon balm is a herbal supplement; it is fit for relieving stress, insomnia, toothaches, headaches and many more.

Lemon balm is a nootropic that relieves anxiety; Its scientific name is Melissa officinalis. It’s one of the calming herbs with a mild lemon scent, Lamiaceae mint plant is its primary source with its most common uses including relieving stress and promoting a night of deep, restful sleep.

The extracts from this herb contain tannins, triterpenes, flavonoids, and phenolic acids that contributors to the many effects of this supplement. 

To use, drink a cup of tea brewed with valerian and lemon balm before bed. You can find loose-leaf or bagged options at your local grocery store or online.


L-theanine is an amino acid that is found in green tea. It has been shown to increase alpha wave activity in the brain, which is associated with a relaxed state of mind. L-theanine has also been shown to increase cognitive performance and reduce anxiety.

Consuming a daily supplement containing up to 400 mg of this amino acid may help improve sleep and relaxation. Animal studies suggest it may be more effective when combined with GABA.

In addition, a 2018 study found that people reported having greater sleep satisfaction after taking 450–900 mg of L-theanine daily for 8 weeks. The study participants had generalized anxiety disorder and were taking antidepressants.

Bacopa monnieri

Bacopa monnieri natural nootropic

Bacopa monnieri is a creeping, aquatic perennial herb that belongs to the family Scrophulariaceae. It is used in traditional Indian medicine for the treatment of a variety of diseases such as asthma, epilepsy, and insomnia. Recent studies have shown that Bacopa monnieri possesses sedative and anxiolytic properties.

In addition, it has been found to improve sleep quality and duration in people with sleep disorders. According to one study, participants who took a bacopa monnieri supplement for eight weeks showed significant improvements in sleep quality. These include reductions in the time it took to fall asleep and an increase in the amount of deep sleep. The benefits of bacopa monnieri for sleep may be due to its ability to reduce anxiety and stress levels.


Magnesium is a mineral involved in hundreds of processes in the human body, and it’s important for brain function and heart health. In addition, magnesium may help quiet the mind and body, making it easier to fall asleep.

One study gave 46 participants 500 mg of magnesium or a placebo daily for 8 weeks. Those in the magnesium group benefited from overall better sleep quality. This group also had higher blood levels of melatonin and renin, both hormones that regulate sleep.

In another small study, participants given a supplement containing 225 mg of magnesium slept better than those given a placebo. However, the supplement also contained 5 mg of melatonin and 11.25 mg of zinc, making it difficult to attribute the effect to magnesium alone.

It’s worth noting that both studies were performed on older adults, who may have had lower blood magnesium levels to start with. It’s uncertain whether these effects would be as strong in individuals with a good dietary magnesium intake.

Can I take nootropics at night for sleeping?

There are many people who take nootropics during the day in order to boost their productivity. But can you also take them at night for sleeping? The answer is yes, you can. In fact, some people find that taking nootropics at night helps them sleep better. This is because nootropics can help to relax the mind and promote better sleep quality.

In addition to taking nootropics, try establishing a regular sleep schedule for your body’s sleep cycle, avoiding caffeine and alcohol before bedtime, and keeping your bedroom dark and quiet. If you still have difficulty sleeping after trying these tips, speak to your doctor about possible solutions.


In conclusion, the best nootropics for sleep in 2022 are those that are effective and safe. However, it is important to do your research before taking any supplements, as some can be dangerous when taken in high doses. Talk to your doctor if you are interested in trying a nootropic for sleep, and be sure to follow the directions prescribed.

Frequently asked questions

Do nootropics help with sleep?

Nootropics are drugs, supplements, or other substances that purportedly improve cognitive function. Many people take nootropics to try to improve their focus, creativity, and memory. A relatively new use for nootropics is as a sleep aid.

Some people report that taking nootropics helps them fall asleep more quickly and sleep more soundly. However, there is very little scientific evidence to support this claim. More research is needed to determine whether nootropics are effective as sleep aids.

Can nootropics make you sleepy?

Nootropics are a type of drug that is often taken to improve cognitive function. They are said to help with memory, focus, and creativity. But can they also make you sleepy?

There is some evidence that suggests nootropics can have a sedative effect. In one study, participants who took a nootropic called piracetam were more likely to fall asleep during a driving simulation test than those who didn’t take the drug.

However, not all studies have found this to be the case. One study found that modafinil – another type of nootropic – actually increased wakefulness and decreased sleepiness.

So it seems that the answer to this question is complex and depends on the individual drug and how it affects each person’s body.

Can I take nootropics before bed?

Nootropics are drugs, supplements, or other substances that improve cognitive function. Most people take them in the morning to increase productivity and alertness, but some people wonder if they can also be taken before bed to improve sleep quality.

The answer is yes – nootropics can be taken before bed to promote better sleep. However, it’s important to note that not all nootropics are sleep-friendly. Some can actually keep you awake, so it’s important to choose the right one for you.

What is a nootropic sleep aid?

Nootropics are substances that are meant to improve cognitive function. This includes memory, creativity, focus, and motivation. One category of nootropics is sleep aids. These are drugs or supplements that are meant to help you fall asleep and stay asleep. There are many different types of sleep aids available. Some are over the counter medications while others are prescription medications.

One type of sleep aid is a nootropic sleep aid. A nootropic sleep aid is a drug or supplement that helps you fall asleep and stay asleep without causing side effects like grogginess or fatigue the next day. Nootropic sleep aids work by increasing the amount of slow-wave sleep you get at night. Slow-wave sleep is the deepest stage of sleep and it is important for restoring energy, repairing muscles, and consolidating memories.